Current Calibrated Parameters

The table presents the ranges of the odds ratios (or hazard ratios) for the parameters influencing transition probabilities in the model. These ranges (lower and upper bound) are derived from studies examining the effect of each parameter on the outcome of interest. For example, the literature indicates that the odds of overdose in males can be up to twice as high as in females; therefore, we defined the odds ratio range for males as [1, 2] in the transition from PU/MU/OUD to overdose. The ‘Mean (literature)’ column shows the average of lower and upper bounds, while the ‘Calibrated’ column displays the value obtained by calibrating the model to overdose death data.

For details on the individual studies used to establish these ranges, click on the hyperlink in the ‘Transition’ column values.

Note: The calibrated values will be updated shortly.