FRED simulates the spread of infectious disease through an artificial population that accurately represents the demographic and geographic distributions in a given city or state, including realistic household, school, and workplace social contact patterns. Each simulation begins with the infection of a few people in the area, and as people interact in households, neighborhoods, schools, and workplaces, the disease may be transmitted from an infectious person to a susceptible person. Simulations are available for every state and county in the United States, and for selected international locations.
More details about the FRED system can be found in our published papers, cited below. Additional publications related to the FRED system can be found on our main publications page.
Grefenstette JJ, Brown ST, Rosenfeld R, Depasse J, Stone NT, Cooley PC, Wheaton WD, Fyshe A,
Galloway DD, Sriram A, Guclu H, Abraham T, Burke DS. FRED (A Framework for Reconstructing
Epidemic Dynamics): An open-source software system for modeling infectious diseases and
control strategies using census-based populations. BMC Public Health, 2013 Oct;13(1),
940. doi: 10.1186/1471-2458-13-940. PubMed PMID:
Liu F, Enanoria WT, Zipprich J, Blumberg S, Harriman K, Ackley SF, Wheaton WD, Allpress JL, Porco TC. The role of vaccination coverage, individual behaviors, and the public health response in the control of measles epidemics: an agent-based simulation for California. BMC Public Health. 2015 May 1;15(1):447. [Epub ahead of print] PubMed PMID: 25928152.
Lukens S, DePasse J, Rosenfeld R, Ghedin E, Mochan E, Brown ST, Grefenstette J, Burke DS, Swigon D, Clermont G. A large-scale immuno-epidemiological simulation of influenza A epidemics. BMC Public Health. 2014 Sep 29;14:1019. doi: 10.1186/1471-2458-14-1019. PubMed PMID: 25266818; PubMed Central PMCID: PMC4194421.
Kumar S, Grefenstette JJ, Galloway DD, Albert SM, and Burke DS. Policies to reduce influenza in the workplace: Impact assessments using an agent-based model. Am J Public Health, 2013 Aug;103(8):1406-11. doi: 10.2105/AJPH.2013.301269. Epub 2013 Jun 13. PubMed PMID: 23763426. Publication data.